

Siwa was featured as a playable character in the 2020 video game Nickelodeon Kart Racers 2: Grand Prix. At the age of 16, she was the youngest contestant to appear on the show until Honey Boo Boo performed in season six. Siwa later competed in season 3 of The Masked Singer as "T-Rex". In 2017, Siwa signed with Nickelodeon and was featured in the film “Blurt!” with Jace Norman and the show “Lip Sync Battle Shorties” with Nick Cannon. In June 2019, the FDA issued a warning about dangerous levels of asbestos in a JoJo Siwa-branded cosmetics kit, prompting “Claire’s” to quit the product. She has also released several books aimed at young children. In 2017, Siwa commented that her bows were a "symbol of power, confidence, believing-ness." Siwa subsequently partnered with the American department store J.C.Penney and released another line of accessories, bedroom decor, and a doll made in her likeness.

Due to the bows' popularity, some stores also began selling similar bows. The line of hair bows, inspired by Siwa’s style, experienced particular success among school kids in the United Kingdom, while some schools banned them for a variety of reasons, including peer pressure, distraction, the impairment of pupils' concentration, and violation of school dress policies. In 2016, Siwa released a line of hair bows in a collaboration with the company “Claire's”. In 2018, Siwa was named the Breakout Artist of the Year by Vivid Seats. In May 2016, Siwa released "Boomerang" for download, and a previous single, "I Can Make U Dance." Both were viewed over 1.3 billion times and received over 5 million likes. Siwa then featured on Dance Moms, beginning with auditioning for Miller's "ALDC" dance competition team in 2014 and was selected in early 2015. She featured on the show with her mother and was eliminated in week 9. Siwa began her career as a top-5 finalist and the youngest contestant on the second season of Abby's Ultimate Dance Competition.
